Drying
What it is
Controlled removal of moisture from dispensed membranes and pads before assembly.
How it works
Membranes and pads are dried under controlled temperature and humidity to fix reagents in place without denaturing antibodies.
Why it matters
Residual moisture destabilizes reagents and shortens shelf life; overdrying can damage antibodies — both affect lot consistency.
Key components
- Controlled temperature and humidity
- Residual moisture control
- Drying validation
Applications
- Fixing dispensed reagents before assembly
- Controlling residual moisture for stability
What affects performance
- Temperature and humidity control
- Drying duration
- Residual moisture level
Limitations
- Overdrying can denature antibodies
- Residual moisture shortens shelf life
Common failure modes
- Overdrying denatures antibodies
- Residual moisture shortens shelf life
- Inconsistent drying across a batch
Frequently Asked Questions
Why is controlled drying important? It fixes reagents without denaturing them and prevents moisture-related instability.
Related knowledge
References
- Posthuma-Trumpie GA, Korf J, van Amerongen A. Lateral flow (immuno)assay: its strengths, weaknesses, opportunities and threats. Anal Bioanal Chem. 2009;393(2):569-582.
- 胶体金免疫层析法定性检测试剂技术审评要点（NMPA technical review）. ivdmat.com.
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Written by the Progene Bio Technical Team · Last reviewed: 2026-09-12