What Is Methadone?

What it is

Methadone is a long-acting opioid used in opioid-substitution therapy (also tested to confirm compliance).

Why it matters

Screened both to detect misuse and to confirm adherence in treatment programs.

Specimen

Urine

Cut-off

300 ng/mL

Interpretation

Positive = methadone detected (presumptive).

Limitations

Detects methadone (not EDDP metabolite); confirm for compliance monitoring.

Related test: Methadone (MTD) Rapid Test — specimen: Urine

Frequently Asked Questions

What does a methadone test detect? Methadone itself (not its EDDP metabolite); used for compliance monitoring.