What Is Hepatitis C Antibodies (Anti-HCV)?

What it is

Anti-HCV antibodies indicate exposure to the hepatitis C virus — current or past infection.

Why it matters

A positive anti-HCV does not confirm active infection; HCV RNA testing is required to confirm.

Specimen

Whole blood / serum / plasma

Interpretation

Reactive = HCV antibodies detected (exposure). Non-reactive = not detected.

Limitations

Anti-HCV indicates exposure, not active infection — confirm with HCV RNA.

Related test: HCV Rapid Test — specimen: WB / S / P

Frequently Asked Questions

Does a reactive HCV antibody mean active infection? No — it indicates exposure; confirm active infection with HCV RNA.

Related knowledge

• Hepatitis hub