What Is Fentanyl?

What it is

Fentanyl is a highly potent synthetic opioid driving the current opioid crisis.

Why it matters

Fentanyl screening is critical due to its potency and prevalence as an adulterant.

Specimen

Urine

Cut-off

Low ng/mL (assay-dependent)

Interpretation

Positive = fentanyl detected (presumptive). Negative = below cut-off.

Limitations

Does not detect all fentanyl analogs; confirm positives by LC-MS/MS.

Related test: Fentanyl (FYL) Rapid Test — specimen: Urine

Frequently Asked Questions

Does a fentanyl test detect all analogs? No — some analogs are not detected; confirm positives by LC-MS/MS.

Related knowledge

• Workplace drug screening